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Table 2 Association of CD44+/CD24- phenotype with clinical characteristics

From: The CD44+/CD24-phenotype is enriched in basal-like breast tumors

Characteristic All tumors (n = 240) Negative (0%) (n = 165) Positive (> 0%) (n = 75) P valuea
Median age (years) 64.1 64.3 63.5 1.0
Menopausal status     0.098
   Premenopausal 42 (18) 24 (15) 18 (24)  
   Postmenopausal 198 (83) 141 (85) 57 (76)  
Tumor size     0.58
   > 20 mm 183 (76) 143 (75) 40 (80)  
   ≤ 20 mm 57 (24) 47 (25) 10 (20)  
Lymph node status     0.19
   Positive (n > 0) 159 (66) 114 (69) 45 (60)  
   Negative (n = 0) 81 (34) 51 (31) 30 (40)  
S-phase fraction     1.0
   High (> 12%) 37 (26) 29 (26) 8 (27)  
   Low (< 12%) 106 (74) 84 (74) 22 (73)  
   Missing 97    
Histologic type     < 0.001
   Ductal 176 (77) 119 (77) 57 (78)  
   Lobular 28 (12) 23 (15) 5 (7)  
   Lobular + ductal 13 (6) 11 (7) 2 (3)  
   Medullary 8 (4) 0 (0) 8 (11)  
   Other 3 (1) 2 (1) 1 (1)  
   Missing 12    
Estrogen receptor     0.45
   Positive (> 25 fmol/mg) 159 (68) 112 (70) 47 (64)  
   Negative 74 (32) 48 (30) 26 (36)  
   Missing 7    
Progesterone receptor     0.89
   Positive (> 25 fmol/mg) 114 (49) 79 (49) 35 (48)  
   Negative 119 (51) 81 (51) 38 (52)  
   Missing 7    
HER2     0.002
   Strong (score = 3) 38 (16) 34 (21) 4 (5)  
   Weak/negative 202 (84) 131 (79) 71 (95)  
Cytokeratin 5/14b     0.012
   Strong 28 (13) 17 (10) 11 (25)  
   Weak/negative 188 (87) 155 (90) 33 (75)  
   Missing 24    
Epidermal growth factor receptorc     
   Strong 27 (11) 12 (7) 15 (20)  
   Weak/negative 210 (89) 150 (93) 60 (80)  
   Missing 3    
Distant metastasis     1.0
   Positive 73 (30) 50 (30) 23 (31)  
   Negative 167 (70) 115 (70) 52 (69)  
  1. Data presented as n (%). aP values were calculated using Fisher's exact test, except for age where the Mann-Whitney U test was used. The missing categories were always excluded. bScoring as previously described [12]. cScoring as previously described [20].