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Table 2 Tumorigenicity of cells from pleural effusion mammospheres

From: Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells

Sample Average size of mammospheres (μm) Percentage of CD44+/CD24low/- cells Tumorigenicity
PE88 20 37 0/3a
PE62 20 13.2 0/3
PE6 30 1.5 0/3
PE43 50 9.9 0/3
06PE8 70 70.6 4/7
06PE6 100 15.3 1/3
PE14 100 All cells CD24- and CD44- 5/7
PE66 130 6.8 1/3
  1. Mice were injected with 5,000 cells from disrupted mammospheres as described in Materials and methods. aThe ratio of mice developing tumours over mice injected. PE, pleural effusion.