Gene | Familial | Controls | RF | p | RR | p |
---|---|---|---|---|---|---|
ATM [1] | 12/443 (2.7%) | 2/521 (0.8%) | 7.1 (1.6–31) | 0.003 | 2.4 (1.5–3.8) | 0.0003 |
BRIP1 [2] | 9/1,212 (0.7%) | 2/2,081 (0.1%) | 7.7 (1.7–36) | 0.002 | 2.0 (1.2–3.2) | 0.01 |
PALB2 [3] | 10/923 (1.1%) | 0/1,084 (0.0%) | - | 0.0004 | 2.3 (1.4–3.9) | 0.0025 |
PALB2 [4] | 3/113 (2.7%) | 6/2,501 (0.2%) | 11.1 (2.8–44) | 0.005 | NA |  |
CHEK2 [5] | 55/1,071 (5.1%) | 18/1,620 (1.1%) | 4.6 (2.7–8) | 0.00000 | 1.7 (1.3–2.2) | 0.0001 |