Table 9 Methylated primary ER-negative and ER-positive tumors: N0 and N1/N2 subgroups
| Â | N0 (n = 76) | N1/N2 (n = 54) | ||||
|---|---|---|---|---|---|---|
Genes | ER negative (n = 38) | ER positive (n = 38) | P valuea | ER negative (n = 27) | ER positive (n = 27) | P valuea |
RASSF1A | 18 (47%) | 36 (95%) | <0.0001 | 18 (67%) | 24 (89%) | 0.0495 |
CCND2 | 16 (42%) | 26 (68%) | 0.021 | 10 (37%) | 19 (70%) | 0.014 |
GSTP1 | 1 (3%) | 7 (18%) | 0.025 | 3 (11%) | 12 (44%) | 0.0062 |
TWIST | 11 (29%) | 17 (45%) | NS | 6 (22%) | 15 (56%) | 0.012 |
APC | 11 (29%) | 19 (50%) | NS | 9 (33%) | 12 (44%) | NS |