Breast Cancer Research

Table 10 Comparison of primary tumor gene methylation status relative to HER2/neu status

From: Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors

	HER2/neu negative (n = 78)		HER2/neu positive (n = 29)		P value^a
Gene	n	%	n	%
RASSF1A	55	71%	27	93%	0.007
CCND2	44	56%	15	52%	NS
GSTP1	10	13%	12	41%	0.0019
TWIST	29	37%	11	38%	NS
APC	26	33%	17	59%	0.0185
NES1	22	28%	7	24%	NS
RARβ2	20	26%	11	38%	NS
CDH1	68	87%	20	67%	0.036

^aχ² test or Fisher's exact test was used appropriately. HER, human epidermal growth factor receptor; NS, not significant.

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ISSN: 1465-542X

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