Skip to main content

Table 1 Characteristics of spontaneous mammary tumors in BALB/c-Trp53+/- mice

From: Estrogen and progesterone induce persistent increases in p53-dependent apoptosis and suppress mammary tumors in BALB/c-Trp53+/-mice

Reproductive history Histopathology Number Frequency ERα-positive
Nulliparous Mammary intra-epithelial neoplasia 1 3.4% 1
  Adenocarcinoma 25 86.2% 3
  Carcinosarcoma 1 3.4% 0
  Adenosquamous 2 6.8% 0
Parous Mammary intra-epithelial neoplasia 2 8.3% 0
  Adenocarcinoma 21 87.5% 7
  Carcinosarcoma 0 0 0
  Adenosquamous 1 4.2% 0
  1. ERα, estrogen receptor-alpha.