Skip to main content

Table 1 Distribution of select risk factors across categories of aspirin use among 126,124 women, National Institutes of Health–AARP Study

From: Nonsteroidal anti-inflammatory drugs and breast cancer risk in the National Institutes of Health–AARP Diet and Health Study

  Frequency of aspirin use in past 12 months
  None <weekly 1–6 times/week 1+/day
Characteristic n %a n %a n %a n %a
Age at second questionnaire
   <57 years 8,178 19.0 8,629 21.7 4,029 20.1 2,936 13.3
   57–60 years 8,317 19.4 8,211 20.6 4,022 20.1 3,566 16.2
   61–64 years 9,750 22.7 9,025 22.7 4,644 23.2 5,132 23.2
   65–68 years 11,085 25.8 9,459 23.8 4,881 24.3 6,607 29.9
   69+ years 5,630 13.1 4,457 11.2 2,481 12.4 3,839 17.4
Race/ethnicity
   Caucasian/non-Hispanic white 38,339 89.2 36,340 91.4 18,561 92.5 20,381 92.3
   Other/unknown 4,621 10.8 3,441 8.6 1,496 7.5 1,699 7.7
Education
   <High school/high school grad 13,537 32.5 10,675 27.5 5,769 29.6 6,857 32.0
   Post-high school+ 28,171 67.5 28,110 72.5 13,696 70.4 14,554 68.0
Body mass index at baseline
   <25 kg/m2 18,461 44.7 18,855 48.9 9,040 46.6 8,718 40.8
   25–30 kg/m2 13,144 31.8 12,331 32.0 6,407 33.0 7,290 34.2
   30+ kg/m2 9,719 23.5 7,342 19.1 3,965 20.4 5,335 25.0
Smoking
   Never 19,321 46.3 18,123 47.0 8,996 46.4 8,984 42.1
   Former 16,758 40.2 15,314 39.7 7,735 39.9 9,184 43.0
   Current 5,630 13.5 5,137 13.3 2,656 13.7 3,193 14.9
Alcoholic drinks
   0 drinks per day 14,515 33.8 9,136 23.0 4,784 23.9 7,009 31.7
   <1 drink per day 23,322 54.3 24,771 62.3 12,299 61.3 12,111 54.9
   1–3 drinks per day 4,037 9.4 4,727 11.9 2,382 11.9 2,297 10.4
   3+ drinks per day 1,086 2.5 1,147 2.9 592 3.0 663 3.0
Self-reported general health
   Excellent/very good/good 36,189 85.6 36,638 93.3 17,869 90.4 17,868 82.4
   Fair/poor 6,094 14.4 2,639 6.7 1,891 9.6 3,814 17.6
Stroke
   No 42,293 98.4 39,557 99.4 19,844 98.9 21,112 95.6
   Yes 667 1.6 224 0.6 213 1.1 968 4.4
Heart disease
   No 39,820 92.7 38,292 96.3 18,924 94.4 17,561 79.5
   Yes 3,140 7.3 1,489 3.7 1,133 5.6 4,519 20.5
High blood pressure
   No 24,240 60.2 25,179 67.7 11,484 61.5 9,502 46.1
   Yes 16,001 39.8 11,997 32.3 7,192 38.5 11,117 53.9
Mammogram in past 3 years
   Once or less 13,226 31.0 12,161 30.8 6,043 30.4 6,496 29.8
   Yes, more than once 29,408 69.0 27,298 69.2 13,827 69.6 15,327 70.2
Age at menarche
   <13 years 21,222 49.8 18,850 47.8 9,679 48.7 11,036 50.4
   13–14 years 17,452 41.0 17,101 43.4 8,407 42.3 8,859 40.5
   15+ years 3,909 9.2 3,492 8.9 1,792 9.0 1,981 9.1
Parity
   Nulliparous 6,253 14.8 5,996 15.3 2,808 14.2 3,089 14.3
   One 4,459 10.6 4,056 10.4 2,009 10.2 2,172 10.0
   Two 11,052 26.2 10,488 26.8 5,290 26.8 5,406 25.0
   Three or more 20,431 48.4 18,578 47.5 9,608 48.7 10,987 50.7
Age at first live birth
   Nulliparous 6,253 14.8 5,996 15.3 2,808 14.2 3,089 14.2
   <20 years 7,385 17.4 6,016 15.3 3,319 16.8 3,895 17.9
   20–24 years 18,472 43.6 17,112 43.6 8,861 44.9 9,800 45.1
   25–29 years 7,636 18.0 7,582 19.3 3,632 18.4 3,739 17.2
   30+ years 2,575 6.1 2,499 6.4 1,129 5.7 1,191 5.5
Age at menopause
   Premenopausal 1,462 3.4 1,738 4.4 742 3.7 445 2.0
   <45 years 2,834 6.6 2,429 6.1 1,266 6.3 1,593 7.2
   45–49 years 6,543 15.2 6,316 15.9 2,997 14.9 3,358 15.2
   50–54 years 11,362 26.4 11,870 29.8 5,415 27.0 5,732 26.0
   55+ years 2,650 6.2 2,555 6.4 1,218 6.1 1,284 5.8
   Surgical menopause 16,770 39.0 13,577 34.1 7,754 38.7 8,975 40.6
   Postmenopausal, age unknown 1,339 3.1 1,296 3.3 665 3.3 693 3.1
Hormone therapy formulation
   Never used 17,328 42.4 15,676 41.2 7,201 37.6 8,371 39.8
   Estrogen therapy only 11,901 29.1 10,157 26.7 5,844 30.5 6,724 32.0
   Estrogen–progestin therapy 11,681 28.6 12,196 32.1 6,100 31.9 5,945 28.3
Moderate/vigorous physical activity during past 10 years
   Never 1,801 4.3 1,033 2.6 545 2.8 878 4.0
   Rarely 4,911 11.6 4,012 10.2 1,986 10.1 2,539 11.7
   <1 hour/week 4,473 10.6 4,102 10.5 2,107 10.7 2,347 10.8
   1–3 hours/week 10,495 24.9 10,085 25.7 5,240 26.6 5,457 25.1
   4–7 hours/week 10,379 24.6 10,438 26.6 5,311 26.9 5,371 24.7
   >7 hours/week 10,100 24.0 9,548 24.3 4,546 23.0 5,122 23.6
Number breast biopsies
   None 32,240 75.8 30,183 76.6 14,985 75.4 16,551 75.8
   One 6,819 16.0 6,175 15.7 3,217 16.2 3,428 15.7
   Two 1,904 4.5 1,666 4.2 926 4.7 997 4.6
   Three or more 1,581 3.7 1,360 3.5 737 3.7 863 4.0
Family history of breast cancer in first degree relative (male or female)
   No 29,536 83.5 27,782 83.8 13,814 83.6 14,930 83.4
   Yes 5,838 16.5 5,356 16.2 2,708 16.4 2,978 16.6
  1. aMissing values were excluded from percentage calculations.