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Table 1 Association between Bcl-2 antanogene-1 (Bag-1), Bcl-2, estrogen receptor, progesterone receptor and Her2/neu and breast cancer-specific survival by Cox univariate analysis with 10-year follow-up

From: Expression patterns and prognostic value of Bag-1 and Bcl-2 in breast cancer

Patient subset Bag-1 (general) Bag-1 (nuclear) Bcl-2 Estrogen receptor Progesterone receptor Her2/neu
Node positive P = 0.006, n = 259, HR = 0.98 (0.97 to 0.995) P = 0.008, n = 259, HR = 0.987 (0.978 to 0.997) P = 0.002, n = 242, HR = 0.99 (0.98 to 0.997) P = 0.0033, n = 270, HR = 0.988 (0.98 to 0.996) P = 0.0012, n = 270, HR = 0.97 (0.96 to 0.99) P = 0.0091, n = 272, HR = 1.02 (1.006 to 1.036)
Node-negative P = 0.67, n = 259, HR = 0.997 (0.98 to 1.01) P = 0.47, n = 259, HR = 0.995 (0.98 to 1.007) P = 0.59, n = 240, HR = 0.998 (0.99 to 1.004) P = 0.57, n = 273, HR = 0.997 (0.98 to 1.008) P = 0.25, n = 266, HR = 0.99 (0.97 to 1.006) P = 0.22, n = 276, HR = 1.02 (0.98 to 1.05)
All patients P = 0.08, n = 518, HR = 0.99 (0.98 to 1.001) P = 0.06, n = 517, HR = 0.99 (0.985 to 1) P = 0.008, n = 482, HR = 0.99 (0.989 to 0.999) P = 0.01, n = 543, HR = 0.99 (0.984 to 0.998) P = 0.0006, n = 536, HR = 0.98 (0.97 to 0.99) P = 0.0007, n = 548, HR = 1.027 (1.012 to 1.04)
  1. Data in bold are significant (P < 0.05). Data in parentheses are the 95% confidence intervals. HR, hazard ratio.