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Table 2 Antiproliferative effect of NVP-AUY922 against primary breast cancer

From: NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models

Cell line IC50 IC70
  nM
MAXF 1162 304 505
MAXF 1322 29 48
MAXF 1384 209 477
MAXF 401 78 295
MAXF 574 >10,000 >10,000
MAXF 583 333 569
  1. The concentrations of NVP-AUY922 that inhibit colony formation by 50% (IC50) or 70% (IC70) were determined (Oncotest GmbH, Freiburg, Germany) [24].