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Table 2 Antiproliferative effect of NVP-AUY922 against primary breast cancer

From: NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models

Cell line

IC50

IC70

 

nM

MAXF 1162

304

505

MAXF 1322

29

48

MAXF 1384

209

477

MAXF 401

78

295

MAXF 574

>10,000

>10,000

MAXF 583

333

569

  1. The concentrations of NVP-AUY922 that inhibit colony formation by 50% (IC50) or 70% (IC70) were determined (Oncotest GmbH, Freiburg, Germany) [24].
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Breast Cancer Research

ISSN: 1465-542X

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