Table 1 Antiproliferative effect of NVP-AUY922 against a panel of human breast cancer cell lines

BT-474

ErbB2⁺/ER⁺

3.1 ± 1.4

17.4 ± 5.2

BT20

ErbB2^-/ER^-

4.0 ± 1.4

18.9 ± 4.8

MDA-MB-157

ErbB2^-/ER^-

126 ± 37

29.5 ± 20.8

MDA-MB-231

ErbB2^-/ER^-

7.0 ± 1.7

2,057 ± 571

MDA-MB-468

ErbB2^-/ER^-

6.3 ± 2.6

1,657 ± 390

SkBr3

ErbB2⁺/ER^-

3.3 ± 0.9

11.9 ± 8.0

MCF-7

ErbB2^-/ER^-

8.8 ± 1.8

69.0 ± 18.3