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Table 1 Limiting dilution tumor formation of CD44+/CD24-/low/ESA+ sorted cells in vivo

From: Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy

Cell type Days Number injected and tumors formed
   1 × 106 1 × 105 1 × 104 1 × 103 1 × 102
SUM159 unsorted 13–100 5/5 5/6 5/8 3/8 0/2
SUM159 CD44+/CD24-/ESA- 20–100 8/10 2/2 1/2 0/8 0/10
SUM159 CD44+/CD24-/low/ESA+ 20–100 - - 2/2 6/6 6/10
SUM1315 unsorted 20–150 2/2 2/2 2/4 0/4 -
SUM1315 CD44+/CD24-/ESA- 25–150 3/4 2/2 0/4 0/10 -
SUM1315 CD44+/CD24-/low/ESA+ 20–150 - - 3/4 7/8 -
SUM149 unsorted 19–150 4/4 3/4 2/4 1/4 0/2
SUM149 CD44+/CD24+/ESA+ 20–150 - 2/2 0/4 0/4 0/6
SUM149 CD44+/CD24-/low/ESA+ 48–150 - 2/2 2/4 6/6 5/6
  1. ESA, epithelial-specific antigen.