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Table 1 Kappa values

From: Carbonic anhydrase IX and response to postmastectomy radiotherapy in high-risk breast cancer: a subgroup analysis of the DBCG82 b and c trials

  One cell ≥ 10% invasive tumour staining ≥ 20% invasive tumour staining
  Obs. 1 Obs. 2 Obs. 1 Obs. 2 Obs. 1 Obs. 2
TMA biopsy versus whole section (central) 0.56 0.51 0.71 0.65 0.68 0.61
TMA biopsy versus whole section (peripheral) 0.52 0.37 0.59 0.59 0.59 0.58
Two different paraffin blocks (central biopsies) 0.72 0.56 0.69 0.86 0.89 0.86
Two different paraffin blocks (peripheral biopsies) 0.66 0.33 0.42 0.49 0.41 -0.07
Whole sections (two different paraffin blocks) 0.70 0.55 0.72 0.74 0.70 0.70
  1. Presented are κ values that describe comparisons between immunohistochemial stainings for carbonic anhydrase IX of 108 tissue microarray biopsies and 54 whole sections from 27 breast carcinomas. The κ values are presented for two observers and using different cut-points for determining positivity.