Figure 3

Cyclooxygenase-2 mRNA expression in mammary gland, mammary carcinomas and in situ carcinomas. Expression of cyclooxygenase-2 (COX-2) mRNA was measured by quantitative real-time PCR. Relative expression of COX-2 mRNA in mammary carcinomas and in situ carcinomas (ISC) in intact (INT) rats, as well as in ISC in ovariectomized (OVX) rats, was compared with baseline expression in normal mammary gland tissues. All expression values normalized to corresponding transcript expressions of rat acidic ribosomal phosphoprotein PO 36B4. The fold changes are shown. Error bars denote standard deviations. Significance levels are indicated.