Table 2 Summary statistics on genotyping results and SNP coverage in ESR1 and EGF for 92 Swedish controls

Number of successfully genotyped SNPs

228^a

104^b

Number of polymorphic SNPs

184

66

Number of common SNPs^c

165

55

Number of SNPs deviating from HWE^d

8

1

Number of SNPs included in study

157

54

Gene size (kb)

295.7

99.4

Sequence coverage of included SNPs (kb)

335.1

145.5

Mean spacing between included SNPs (kb)

2.1

2.7

Median spacing between included SNPs (kb)

1.8

2.3

Number of tagSNPs selected

52

15

Average tagSNP prediction of common SNPs included in study (R²)^c

0.998

0.987

Coverage evaluation^e

Average prediction of dropped SNPs (R²)

0.997

0.948

Percentage of R² values ≥ 0.7

100

96.3