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Table 1 Selected characteristics of the cases and controls participating in the present and parent breast cancer study

From: ESR1 and EGFgenetic variation in relation to breast cancer risk and survival

 

Present

Parent

Characteristic

No. of cases/controls

Cases/controls

No. of cases/controls

Cases/controls

  

Mean:

 

Mean:

Age (years)

1,590/1,518

63.4/63.1

2,817/3,111

63.4/64.3

Age at menopause (years)

1,580/1,505

50.4/50.0

2,802/3,093

50.4/50.0

Recent BMI (kg/m2)a

1,581/1,497

25.8/25.5

2,802/3,065

25.8/25.5

Age at first birth (years)

1,352/1,370

25.4/24.7

2,373/2,753

25.3/24.6

Parity

1,590/1,518

1.8/2.2

2,817/3,110

1.8/2.1

Duration of menopausal hormone use (years)

 

Percentage:

 

Percentage:

0

1,058/1,086

67.2/72.7

1,978/2,467

71.4/80.8

< 4

206/190

13.1/12.7

405/330

14.6/10.8

≥ 4

311b/217b

19.8b/14.5b

389/256

14.0/8.4

Self-reported diabetes mellitus (yes/no)

1,588/1,402

9.0b/7.8b

2,810/2,652

6/6.1

Family history (yes/no)c

1,551/1,380

16.1/9.3

2,744/2,607

16.0/9.2

High NPI (≤ 4/> 4)

975/-

55.7/-

 

-/-

  1. BMI, body mass index; NPI, Nottingham Prognostic Index. a At 1 year prior to diagnosis. b Long-term users of menopausal hormones and women with diabetes mellitus were oversampled. c Family history is defined as having at least one first degree relative with breast cancer.