Figure 1
From: ESR1 and EGFgenetic variation in relation to breast cancer risk and survival
Association of 52 tagging single nucleotide polymorphisms (tagSNPs) in ESR1 with breast cancer risk, Nottingham Prognostic Index (NPI) and breast cancer survival. Left column: breast cancer risk. Middle column: NPI (case-only analysis). Right column: breast cancer survival. Squares and horizontal lines represent odds and hazard (survival analysis) ratios (change in risk with each addition of the rare allele) and their confidence intervals. Sizes of the squares reflect the minor allele frequencies. NPI was categorised into ≤ 4 or > 4.