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Table 3 Associations between ERBB2 and AP-2α and/or YY1 levels determined by immunohistochemistry

From: The combined immunodetection of AP-2α and YY1 transcription factors is associated with ERBB2 gene overexpression in primary breast tumors

  

ERBB2 expression (percentage)

 
 

n

0/1+

2+

3+

P value

AP-2α expression

       

0.003

   Low

32

19

(59)

5

(16)

8

(25)

 

   High

23

4

(17)

12

(52)

7

(31)

 

YY1 expression

       

0.318

   Low

30

15

(50)

7

(23)

8

(27)

 

   High

25

8

(32)

10

(40)

7

(28)

 

Combination

       

0.016

   AP-2α lo/YY1 lo

26

14

(54)

4

(15)

8

(31)

 

   AP-2α lo/YY1 hi or AP-2α hi/YY1 lo

10

6

(60)

4

(40)

0

(0)

 

   AP-2α hi/YY1 hi

19

3

(16)

9

(47)

7

(37)

 
  1. AP-2α, activator protein 2 alpha; hi, high expression; lo, low expression; YY1, Yin Yang 1.
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Breast Cancer Research

ISSN: 1465-542X

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