Table 1 Clinicopathological data of the patients and their relationships with ERBB2 expression
Characteristic | n | (Percentage) | ERBB2 expression (percentage) | P value | |||
|---|---|---|---|---|---|---|---|
(0/1+/2+) | (3+) | ||||||
Number of patients | 55 | (100) | 40 | (73) | 15 | (27) | |
Tumor size | NS | ||||||
T1 | 20 | (36) | 16 | (80) | 4 | (20) | |
T2 | 29 | (53) | 20 | (69) | 9 | (31) | |
T3 | 6 | (11) | 4 | (67) | 2 | (33) | |
Lymph node status | NS | ||||||
Negative | 33 | (60) | 24 | (73) | 9 | (27) | |
Positive | 22 | (40) | 16 | (73) | 6 | (27) | |
Grade | |||||||
Not determined | 3 | (5) | / | ||||
I | 12 | (22) | 29 | (83) | 6 | (17) | 0.060 |
II | 23 | (42) | |||||
III | 17 | (31) | 10 | (59) | 7 | (41) | |
Histological type | NS | ||||||
Ductal | 40 | (73) | 28 | (70) | 12 | (30) | |
Lobular | 7 | (13) | 5 | (71) | 2 | (29) | |
Other | 8 | (14) | 7 | (87) | 1 | (13) | |
ER status | 0.035 | ||||||
Positive | 42 | (76) | 34 | (81) | 8 | (19) | |
Negative | 13 | (24) | 6 | (46) | 7 | (54) | |
PR status | 0.022 | ||||||
Positive | 32 | (58) | 27 | (84) | 5 | (16) | |
Negative | 23 | (42) | 13 | (57) | 10 | (43) | |
Menopausal status | NS | ||||||
Premenopausal | 9 | (16) | 8 | (89) | 1 | (11) | |
Postmenopausal | 46 | (84) | 32 | (70) | 14 | (30) | |
Ki67 | 0.018 | ||||||
Low | 29 | (53) | 25 | (86) | 4 | (14) | |
High | 26 | (47) | 15 | (58) | 11 | (42) | |
p53 | 0.052 | ||||||
Low | 46 | (84) | 36 | (78) | 10 | (22) | |
High | 9 | (16) | 4 | (44) | 5 | (56) | |