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Table 3 Multivariate analysis for relapse-free survival in the test set cohort of baseline prognostic factors

From: Can clinically relevant prognostic subsets of breast cancer patients with four or more involved axillary lymph nodes be identified through immunohistochemical biomarkers? A tissue microarray feasibility study

Factor

Hazard ratio (95% CI)

P

Grade (3 versus 1 or 2)

1.20 (0.84–1.70)

0.3

Tumor size, cm

 

0.03

   >2–5 versus 0–2

1.62 (1.12–2.33)

0.01

   >5 versus 0–2

1.23 (0.71–2.12)

0.5

Pathological ER statusa

0.53 (0.37–0.76)

0.0005

Lymphovascular invasion

1.32 (0.84–2.09)

0.2

Percentage of positive nodes

 

0.09

   >50–99 versus 0–50

1.22 (0.87–1.73)

0.3

   100 versus 0–50

1.62 (1.05–2.50)

0.03

  1. Multivariate Cox regression analysis was performed inclusive of those factors reaching statistical significance in univariate analysis. ER, estrogen receptor; CI, confidence interval.
  2. aPathological ER status at diagnosis.