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Table 5 Estimation of relative risk of reduction of disease-free survival in African-American and Latina women with breast cancer using multivariate analysis

From: Clinical significance of Akt and HER2/neu overexpression in African-American and Latina women with breast cancer

 

Relative risk

95% CI

P value

Tumor size (≥ 5 cm versus <5 cm)

2.1

1.4–4.0

0.03

Lymph node (positive versus negative)

2.2

1.0–4.8

0.05

ER/PR status (negative versus positive)

1.9

1.0–3.3

0.04

pAkt status (high versus low)

2.5

1.3–4.8

0.006

HER2/neu status (positive versus negative)

1.7

1.0–3.3

0.05

Age (<50 years versus ≥ 50 years)

0.9

0.5–1.7

0.54

Ethnicity (African-American versus Latina)

1.2

0.7–2.2

0.54

  1. CI, confidence interval; ER/PR, estrogen receptor/progesterone receptor; HER2/neu positive, HER2/neu 3+ examined by immunohistochemistry (IHC); HER2/neu negative, HER2/neu 2+ and HER2/neu 1+/negative by IHC; pAkt high, the pAkt index level above median level (>36); pAkt low, the pAkt index level less than or equal to median level (≤36).
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Breast Cancer Research

ISSN: 1465-542X

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