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Table 5 Estimation of relative risk of reduction of disease-free survival in African-American and Latina women with breast cancer using multivariate analysis

From: Clinical significance of Akt and HER2/neu overexpression in African-American and Latina women with breast cancer

  Relative risk 95% CI P value
Tumor size (≥ 5 cm versus <5 cm) 2.1 1.4–4.0 0.03
Lymph node (positive versus negative) 2.2 1.0–4.8 0.05
ER/PR status (negative versus positive) 1.9 1.0–3.3 0.04
pAkt status (high versus low) 2.5 1.3–4.8 0.006
HER2/neu status (positive versus negative) 1.7 1.0–3.3 0.05
Age (<50 years versus ≥ 50 years) 0.9 0.5–1.7 0.54
Ethnicity (African-American versus Latina) 1.2 0.7–2.2 0.54
  1. CI, confidence interval; ER/PR, estrogen receptor/progesterone receptor; HER2/neu positive, HER2/neu 3+ examined by immunohistochemistry (IHC); HER2/neu negative, HER2/neu 2+ and HER2/neu 1+/negative by IHC; pAkt high, the pAkt index level above median level (>36); pAkt low, the pAkt index level less than or equal to median level (≤36).