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Table 4 pAkt level in relation to distant metastases and local recurrence

From: Clinical significance of Akt and HER2/neu overexpression in African-American and Latina women with breast cancer

 

Distant metastases

P value

Local recurrence

P value

 

Yes (%)

No (%)

 

Yes (%)

No (%)

 

HER2+/High pAkt

61.9

38.1

0.007

12.5

87.5

0.259

HER2+/Low pAkt

21.4

78.6

 

18.2

81.8

 

HER2-/High pAkt

56.3

43.7

 

7.1

92.9

 

HER2-/Low pAkt

31.3

68.7

 

0

100

 
  1. HER2+, HER2/neu 3+ determined by immunohistochemistry (IHC); HER2-, HER2/neu 2+ and 1+ and negative determined by IHC; High pAkt, pAkt level above median level (>36); Low pAkt, pAkt level of less than or equal to 36.