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Table 3 pAkt expression in relation to patient characteristics and tumor pathology

From: Clinical significance of Akt and HER2/neu overexpression in African-American and Latina women with breast cancer

  Number pAkt P value
   Median Range  
Total 141 36.0 0–255.0  
Ethnicity     
   African-American 72 35.7 0–174.0  
   Latina 69 36.6 0–255.0 0.992
Age at diagnosis     
   <50 years 73 31.0 0–255.0  
   ≥ 50 years 68 39.0 0–174.0 0.678
Tumor size     
   <5 cm 90 32.2 0–174.0  
   ≥ 5 cm 51 36.6 0–255.0 0.117
Lymph node status     
   Positive 89 45.0 0–255.0  
   Negative 52 27.5 0–135.0 0.001
AJCC stage     
   0–II 88 33.3 0–174.0  
   III–IV 53 42.0 0–255.0 0.160
Histological grade     
   Well to moderately differentiated 44 30.0 0–174.0  
   Poorly differentiated 97 40.8 0–255.0 0.094
ER/PR status     
   ER/PR+ 81 30.0 0–255.0  
   ER/PR- 60 47.3 0–170.0 0.164
HER2/neu status (IHC)     
   Positive 46 44.5 0–255.0  
   Negative 95 30.0 0–168.9 0.009
  1. AJCC, American Joint Committee on Cancer; ER/PR, estrogen receptor/progesterone receptor; HER2/neu negative, HER2/neu 2+ and 1+ and negative determined by immunohistochemistry (IHC); HER2/neu positive, HER2/neu 3+ determined by IHC.