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Table 5 Correlation analysis of hypoxia-inducible factor 1α (HIF-1α) expression and standard clinicopathological parameters

From: Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer

  HIF-1α-positive (n = 125) HIF-1α-negative (n = 91) P value
Median patient age (years) 59 59 0.59
Median tumour size (mm) 20 20 0.23
Tumour grade    0.52
   1 22 15  
   2 44 22  
   3 27 23  
Nodal status    0.02
   Negative 62 31  
   Positive 63 60  
Oestrogen receptor status    0.90
   Negative 98 72  
   Positive 27 19  
Human epidermal growth factor receptor 2 status    0.77
   Negative 12 11  
   Positive 87 70  
  1. n < 216 data not available.