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Figure 2 | Breast Cancer Research

Figure 2

From: Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer

Figure 2

Kaplan–Meier curves of disease-free survival. (a) Stratifying patients by hypoxia-inducible factor-1α (HIF-1α) expression. (b) Stratifying patients by cytoplasmic factor-inhibiting hypoxia-inducible factor-1 (FIH-1) expression. (c) Stratifying patients by nuclear FIH-1 expression. (d) Stratifying patients by exclusive nuclear FIH-1 expression (functional), and by exclusive cytoplasmic FIH-1 expression and FIH-1 negativity (nonfunctional). (e) Stratifying patients by exclusive cytoplasmic FIH-1 expression (nonfunctional), and by exclusive nuclear FIH-1 expression (functional). (f) Stratifying patients by exclusive cytoplasmic FIH-1 expression and tumours negative for FIH-1.

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