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Figure 5 | Breast Cancer Research

Figure 5

From: Anticlusterin treatment of breast cancer cells increases the sensitivities of chemotherapy and tamoxifen and counteracts the inhibitory action of dexamethasone on chemotherapy-induced cytotoxicity

Figure 5

Effects of combined treatment with anticlusterin antibody and paclitaxel or doxorubicin on cytotoxicity of the MDA-MB-231 and MCF-7 cell lines. Cells were treated with the antibody for 1 day (30 μg/mL). After antibody treatment, the medium was replaced in some wells with medium containing 10-7 M paclitaxel or doxorubicin for 1 day. Cell viability was determined by trypan blue exclusion test. Each data point represents the mean percentages of at least three independent experiments ± standard error of the mean. **p < 0.01. Differences were calculated comparing the combined treatment with anticlusterin antibody or chemotherapeutic agent alone. D, doxorubicin; P, paclitaxel.

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