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Table 2 Genotype and allele proportions for breast cancer risk associated with BsmI and Poly(A) genotypes

From: Vitamin D receptor polymorphisms and breast cancer risk in a large population-based case-control study of Caucasian and African-American women

Genotype   Controlsa (n [%]) Allele frequency Casesa (n [%]) Allele frequency ORb (95% CI)
BsmI       
   All B/B 308 (21.7)   345 (20.6)   1.0 (referent)
  B/b 539 (37.2) B 0.41 606 (37.2) B 0.40 1.1 (0.9 to 1.3)
  b/b 564 (41.0) b 0.59 670 (42.2) b 0.60 1.1 (0.9 to 1.4)
  any b 1,103 (78.3)   1,276 (79.4)   1.2 (0.9 to 1.3)
   Caucasian B/B 258 (27.3)   278 (24.5)   1.0 (referent)
  B/b 371 (38.2) B 0.46 432 (37.9) B 0.43 1.1 (0.9 to 1.4)
  b/b 336 (34.5) b 0.54 426 (37.5) b 0.57 1.2 (0.9 to 1.6)
  any b 707 (84.4)   858 (84.8)   1.2 (0.9 to 1.4)
   African American B/B 50 (11.7)   67 (13.3)   1.0 (referent)
  B/b 168 (35.5) B 0.30 174 (36.0) B 0.32 0.9 (0.6 to 1.4)
  b/b 228 (52.8) b 0.70 244 (50.7) b 0.68 0.9 (0.5 to 1.3)
  any b 390 (88.4)   406 (86.7)   0.9 (0.6 to 1.3)
Poly(A)       
   All S/S 176 (12.6)   202 (13.1)   1.0 (referent)
  L/S 651 (45.9) S 0.36 713 (44.2) S 0.35 0.9 (0.7 to 1.2)
  L/L 575 (41.4) L 0.64 665 (42.7) L 0.65 1.0 (0.8 to 1.3)
  any L 1,226 (87.4)   1,378 (86.9)   1.0 (0.8 to 1.2)
   Caucasian S/S 149 (15.6)   167 (15.2)   1.0 (referent)
  L/S 402 (49.5) S 0.39 532 (46.1) S 0.38 1.0 (0.7 to 1.3)
  L/L 354 (34.9) L 0.61 440 (38.7) L 0.62 1.1 (0.8 to 1.5)
  any L 836 (72.7)   972 (75.5)   1.0 (0. 8 to 1.4)
   African American S/S 27 (6.8)   35 (8.9)   1.0 (referent)
  L/S 169 (39.0) S 0.27 181 (40.5) S 0.28 0.8 (0.5 to 1.5)
  L/L 221 (54.2) L 0.73 225 (50.6) L 0.72 0.7 (0.4 to 1.3)
  any L 396 (93.2)   418 (91.1)   0.8 (0.4 to 1.4)
  1. aProportions are weighted for age, race, study site, and first-degree family history sampling probabilities. bOdds ratio (OR) adjusted for age, race, study site, and sampling weights. CI, confidence interval.