Figure 3From: Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants?Varied capacity of C-terminal BRCA1 variants to form foci in response to DNA damage. (a) Post-ionising radiation (IR) nuclear foci formation in cells co-transfected with the nuclear chaperone BARD1. (b) Summary of nuclear foci formation data in untreated cells and cells treated with IR. UV, unclassified variant; WT, wild-type.Back to article page