Figure 1

Lobular neoplasia. The classification of lobular neoplasia is determined by the extent of disease both within the terminal duct lobular units and within the breast in general. The clinical entities that fall into the classification of lobular neoplasia include (a) minimal atypical lobular hyperplasia (magnification: 200×), (b) atypical lobular hyperplasia (ALH; 200×), (c) ALH with ductal involvement by cells of ALH (200×), (d) lobular carcinoma in situ (100×), and (e) invasive lobular carcinoma (200×). All lesions were stained with hematoxylin and eosin.