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Table 1 Inter-laboratory correlation between FISH and CISH

From: Chromogenic in situ hybridisation for the assessment of HER2 status in breast cancer: an international validation ring study

  CISH (number of signals)  
FISH HER2/CEP17 ratio <5 5 6 >6 No signal n
<2.0 91 3 0 3 3 100
2.0–4.0 11 4 5 15 0 35
>4.0 1 2 3 70 0 76
Total 103 6 8 88 3 211
  1. CISH, chromogenic in situ hybridisation; FISH, fluorescence in situ hybridisation; HER2, human epidermal growth factor receptor 2.