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Table 2 Two-year average annual breast cancer incidence and mortality rates in non-Hispanic white women

From: Recent changes in breast cancer incidence and risk factor prevalence in San Francisco Bay area and California women: 1988 to 2004

  San Francisco Bay area The rest of California
  2000–2001
Rate (95% CI)
2003–2004
Rate (95% CI)
2000–2001
Rate (95% CI)
2003–2004
Rate (95% CI)
Mortality rate 27.4 (25.7–29.2) 26.5 (24.9–28.3) 27.8 (27.1–28.6) 25.4 (24.6–26.1)
In situ incidence rate 35.6 (33.6–37.7) 33.2 (31.3–35.2) 30.5 (29.7–31.4) 29.5 (28.7–30.4)
Invasive incidence rate 160.0 (155.9–164.3) 140.8 (136.9–144.8) 151.7 (149.9–153.6) 135.1 (133.4–136.9)
   Histologic subtypea     
Ductal 110.9 (107.5–114.5) 97.0 (93.7–100.3) 98.9 (97.4–100.4) 88.4 (87.0–89.8)
With lobular component 29.6 (27.8–31.5) 26.9 (25.2–28.7) 30.4 (29.6–31.2) 27.0 (26.2–27.8)
   Age at diagnosis (years)a     
<40 13.1 (11.5–15.0) 14.0 (12.1–16.1) 13.0 (12.2–13.9) 13.0 (12.2–13.9)
40–69 305.5 (295.4–315.8) 263.1 (253.9–272.5) 287.3 (282.8–291.9) 255.5 (251.3–259.7)
≥70 535.3 (511.7–559.8) 475.7 (452.4–499.9) 511.6 (501.3–522.0) 447.8 (438.0–457.7)
   ER/PR statusa     
ER+/PR+ 96.0 (92.7–99.3) 83.7 (80.7–86.8) 76.0 (74.7–77.3) 65.9 (64.7–67.2)
ER+/PR- 19.5 (18.0–21.0) 15.3 (14.1–16.7) 15.9 (15.3–16.5) 14.1 (13.5–14.6)
ER-/PR+ 2.3 (1.8–2.9) 1.0 (0.7–1.4) 1.9 (1.7–2.1) 1.3 (1.1–1.5)
ER-/PR- 21.6 (20.1–23.3) 20.3 (18.8–21.9) 20.5 (19.8–21.3) 19.6 (18.9–20.2)
Missing 20.7 (19.3–22.3) 20.3 (18.9–21.9) 37.4 (36.5–38.4) 34.3 (33.4–35.1)
   Stage at diagnosisa     
Localized 103.4 (100.1–106.8) 93.1 (89.9–96.4) 95.0 (93.5–96.5) 84.6 (83.3–86.0)
Regional 48.4 (46.1–50.8) 40.5 (38.4–42.7) 47.8 (46.8–48.9) 42.0 (41.0–43.0)
Distant 6.0 (5.2–6.9) 5.3 (4.5–6.1) 5.4 (5.0–5.8) 5.5 (5.2–5.9)
Unstaged/Not available 2.3 (1.8–2.8) 1.5 (1.1–1.9) 3.4 (3.2–3.7) 2.2 (2.0–2.5)
   Tumor size     
<2 cm 93.4 (90.2–96.7) 82.6 (79.6–85.7) 84.8 (83.4–86.2) 73.9 (72.6–75.2)
≥2 cm 58.1 (55.6–60.7) 51.6 (49.2–54.1) 58.2 (57.0–59.4) 53.5 (52.4–54.6)
Unknown 8.5 (7.6–9.5) 6.1 (5.3–6.9) 8.8 (8.3–9.2) 7.1 (6.7–7.5)
  1. All rates per 100,000 and age-adjusted to the 2000 US age standard. aInvasive breast cancer. CI, confidence interval; ER, estrogen receptor. Data from the California Cancer Registry.