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Figure 5 | Breast Cancer Research

Figure 5

From: BP1 transcriptionally activates bcl-2and inhibits TNFα-induced cell death in MCF7 breast cancer cells

Figure 5

Model for BP1-mediated disruption of caspase activation after TNFα treatment. Arrows indicate the three points (a, b and c) at which Beta Protein 1 (BP1) may impact apoptosis. Bid, BH3 interacting domain death agonist; CYT C, cytochrome c; FADD, Fas (TNFRSF6)-associated via death domain; PARP, Poly(ADP-Ribose) Polymerase; t-Bid, truncated Bid; TNFR1, TNF receptor 1; TRADD, TNFRSF1A-associated via death domain.

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Breast Cancer Research

ISSN: 1465-542X

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