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Table 1 Gene set enrichment analysis results for the gene list tested

From: Aging impacts transcriptomes but not genomes of hormone-dependent breast cancers

Gene set Comparison
  Old over young cohort Progesterone receptor-negative over progesterone receptor-positive tumors ERBB2-negative over ERBB2-positive tumors
  Enrichment score Nominal P value FWER P value Enrichment score Nominal P value FWER P value Enrichment score Nominal P value FWER P value
MAPK upregulated 0.44 0.05 0.13 0.28 0.49 0.67 0.28 0.46 0.65
MAPK downregulated -0.36 0.17 0.4 -0.31 0.33 0.57 0.26 0.26 0.68
Luminal markers 0.31 0.72 0.79 -0.63 0.1 0.15 0.48 0.38 0.57
Proliferation markers -0.85 0.006 0.011 0.62 0.32 0.38 -0.83 0.01 0.02
  1. Gene sets showing significant enrichment after adjustment for multiple gene set testing (family-wise error rate (FWER) P < 0.05) are presented in bold.