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Table 3 Mean dense breast area for quintiles of sex steroids and sex hormone binding globulin (n = 775)

From: No relationship between circulating levels of sex steroids and mammographic breast density: the Prospect-EPIC cohort

  Quintile 1 Quintile 2 Quintile 3 Quintile 4 Quintile 5 P value for trend
Oestronea 27.4 (25.3–29.5) 27.3 (25.1–29.6) 27.0 (25.0–29.1) 26.5 (24.6–28.5) 25.2 (23.3–27.2) 0.09
Oestradiolb 27.9 (25.8–30.0) 27.7 (25.7–29.8) 24.3 (22.4–26.3) 27.2 (25.2–29.4) 26.1 (24.2–28.1) 0.27
Free oestradiolc 27.8 (25.7–29.9) 27.3 (25.2–29.4) 26.0 (24.0–28.0) 26.3 (24.3–28.3) 25.9 (23.9–28.0) 0.20
Dehydroepiandrosterone sulfated 27.8 (25.7–29.9) 26.0 (24.0–28.1) 26.5 (24.5–28.6) 26.2 (24.2–28.3) 26.7 (24.7–28.8) 0.68
Androstenedionee 26.8 (24.8–28.9) 27.1 (25.1–29.3) 25.5 (23.5–27.6) 28.2 (26.2–30.3) 25.5 (23.5–27.5) 0.44
Testosteronef 27.1 (25.0–29.2) 27.5 (25.5–29.6) 25.9 (23.9–28.0) 26.3 (24.3–28.3) 26.4 (24.4–28.5) 0.53
Free testosteroneg 28.7 (26.6–30.8) 25.6 (23.7–27.7) 25.3 (23.4–27.4) 27.5 (25.4–29.6) 26.1 (24.1–28.1) 0.36
Sex hormone binding globulinh 26.3 (24.2–28.4) 26.2 (24.2–28.2) 25.5 (23.6–27.5) 27.7 (25.6–29.8) 27.5 (25.5–29.7) 0.22
  1. Data presented as the mean (95% confidence interval). aQuintile cutoff points: 7.45, 12, 15, 20 and 29 pg/ml. bQuintile cutoff points: 4.45, 6.4, 8.2, 10.0 and 14 pg/ml. cQuintile cutoff points: 0.12, 0.18, 0.24, 0.31 and 0.45 pg/ml. dQuintile cutoff points: 188, 333, 479, 666 and 1,041 ng/ml. eQuintile cutoff points: 0.19, 0.36, 0.50, 0.67 and 1.10 ng/m. fQuintile cutoff points: 0.13, 0.20, 0.26, 0.33 and 0.47 ng/m. gQuintile cutoff points: 2.29, 3.98, 5.48, 7.50 and 11.36 pg/ml. hQuintile cutoff points: 6.2, 15, 21, 28 and 43 nmol/l.