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Table 5 Median values and median percentage change from baseline for serum lipid profiles (mITT population)

From: Effects of steroidal and nonsteroidal aromatase inhibitors on markers of bone turnover in healthy postmenopausal women

Lipid Exemestane (n= 20) Letrozole (n= 20) Anastrozole (n= 19) Placebo (n= 20)
LDL-C (mmol/L)
   Baseline 4.2 4.2 4.2 3.8
   Week 12, % change -11 -4.5 -12 -6.1
   Week 24, % change -2.6 -4.2 -3.0 2.4
   Week 36, % change 1.9 0.25 -5.7 -5.8
HDL-C (mmol/L)
   Baseline, median 1.4 1.5 1.4 1.4
   Week 12, % change -4.4 9.0 1.7 -3.5
   Week 24, % change -13 -2.4 -4.4 -6.3
   Week 36, % change -6.9 -2.4 -2.5 -6.8
Total cholesterol (mmol/L)
   Baseline, median 6.1 6.1 6.3 5.9
   Week 12, % change -6.8 -1.8 -3.7 -2.6
   Week 24, % change 0.78 1.2 -0.68 0.75
   Week 36, % change 1.3 -1.9 -5.8 -6.4
Triglycerides (mmol/L)
   Baseline, median 1.1 1.2 1.2 1.0
   Week 12, % change -21 6.6 -10 -1.6
   Week 24, % change 1.7 4.6 6.3 -7.0
   Week 36, % change -1.1 -5.4 -3.5 -0.28
  1. HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; mITT = modified intent to treat.