Figure 3

Network of functional association between IFN-γ gene and other GATMs generated by Ingenuity database analysis. ADIPOQ, CCL22, IFNG, IL1B, PPARA, RXRG, MSR1, GAD1 and TAP1 are genes associated with proliferation, whereas USP18 and CDH13 are genes linked to growth. ASS, DUSP5, ADCY5 and UBD are genes associated with apoptosis/survival. CXCR6, CXCL16 and CNR2 are genes associated with chemotaxis/trafficking; KLRK1 and HCST are associated with cytolysis/cytotoxicity; and RARRES1 and CD36 are linked to migration. All of the other genes have unknown cell functions. Genes are shown by their symbols. GATM, gene associated with mammary tumour microenvironment; IFN, interferon.