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Table 1 Quantitative Wilms' tumor 1 suppressor gene (WT1) expression in stable transfectant of breast cancer cells with quantitative real-time PCR

From: The zinc finger domain of Wilms' tumor 1 suppressor gene (WT1) behaves as a dominant negative, leading to abrogation of WT1 oncogenic potential in breast cancer cells

 

MCF-7 cells

MDA468 cells

Transfected plasmid

Control

ZF - KTS

Control

ZF - KTS

Mouse WT1–ZF

1 ± 0.2

395 ± 66

1 ± 0.2

1894 ± 136

Human WT1

1 ± 0.1

0.43 ± 0.07

1 ± 0.2

0.28 ± 0.16

  1. ZF - KTS, zinc finger domain lacking the lysine–threonine–serine insert of WT1.
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Breast Cancer Research

ISSN: 1465-542X

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