Figure 5From: Adenovirus type 5 E1A-induced apoptosis in COX-2-overexpressing breast cancer cellsCelecoxib-induced apoptosis of MDA-MB-231-E1A and MDA-MB-435-E1A cells depends on PGE2 or PGF2α. Treatment of MDA-MB-231-E1A and MDA-MB-435-E1A stable transfectants with 0 or 40 μM celecoxib (CLX) plus 10 μM of either PGE2or PGF2α for 5 days blunted sensitivity to celecoxib in both cell lines.Back to article page