Skip to main content

Table 2 Genes upregulated by AI treatment

From: Molecular response to aromatase inhibitor treatment in primary breast cancer

ID

Symbol

Description

Unigene

Fold

LFDR

HSI022G08

LUM

Lumican

Hs.406475

2.87

0.11

HSI101E05

ODF2L

Outer dense fiber of sperm tails 2-like

Hs.149360

2.80

0.07

HSI027H04

IGJ

Immunoglobulin J polypeptide

Hs.381568

2.73

0.07

HSI082D05

RNH1

Ribonuclease/angiogenin inhibitor 1

Hs.530687

2.51

0.00

HSI056B04

COL3A1

Collagen, type III, alpha 1

Hs.443625

2.50

0.00

HSI182D05

MRC1L1

Mannose receptor, C type 1

Hs.461247

2.45

0.06

HSI067F08

C21orf70

Chromosome 21 open reading frame 70

Hs.410830

2.44

0.00

HSI127E04

CALD1

Caldesmon 1

Hs.490203

2.37

0.11

HSI030C06

PTPRC

Protein tyrosine phosphatase, receptor type, C

Hs.192039

2.36

0.11

HSI067H02

ASPN

Asporin (LRR class 1)

Hs.435655

2.34

0.00

HSI066B08

COL14A1

Collagen, type XIV, alpha 1 (undulin)

Hs.409662

2.28

0.11

HSI049B12

COL1A2

Collagen, type I, alpha 2

Hs.489142

2.28

0.00

HSI049G07

DCN

Decorin

Hs.156316

2.28

0.00

HSI067E05

MRC1L1

Mannose receptor, C type 1

Hs.461247

2.22

0.05

HSI101D05

IFT122

Intraflagellar transport 122 homolog (Chlamydomonas)

Hs.477537

2.17

0.03

HSI183E05

PDGFRA

Platelet-derived growth factor receptor, alpha

Hs.74615

2.14

0.09

HSI031A12

FSTL1

Follistatin-like 1

Hs.269512

2.12

0.00

HSI183H01

COL5A2

Collagen, type V, alpha 2

Hs.445827

2.11

0.00

HSI055A11

ECM2

Extracellular matrix protein 2

Hs.117060

2.08

0.09

HSI018G02

SPON1

Spondin 1, extracellular matrix protein

Hs.445818

2.06

0.00

HSI183B01

PDGFRA

Platelet-derived growth factor receptor, alpha

Hs.74615

2.04

0.01

HSI037C02

CPVL

Carboxypeptidase, vitellogenic-like

Hs.233389

2.03

0.06

HSI062B08

SAS10

Disrupter of silencing 10

Hs.322901

2.01

0.00

HSI129E10

ADAM12

ADAM metallopeptidase domain 12 (meltrin alpha)

Hs.386283

2.00

0.00

HSI183G08

RGS1

Regulator of G-protein signalling 1

Hs.75256

1.98

0.18

HSI054F01

VIM

Vimentin

Hs.533317

1.97

0.00

HSI048C08

CTGF

Connective tissue growth factor

Hs.410037

1.97

0.00

HSI183G05

SPARC

Secreted protein, acidic, cysteine-rich (osteonectin)

Hs.111779

1.96

0.00

HSI139G09

ADAMTS2

ADAM metallopeptidase with thrombospondin motif 2

Hs.23871

1.96

0.00

HSI018D05

FBLN1

Fibulin 1

Hs.24601

1.95

0.00

HSI040E08

DUSP1

Dual specificity phosphatase 1

Hs.171695

1.95

0.00

HSI082C05

MAN1A1

Mannosidase, alpha, class 1A, member 1

Hs.102788

1.94

0.01

HSI098G12

RARRES1

Retinoic acid receptor responder 1

Hs.131269

1.94

0.00

HSI044C09

SAT

Spermidine/spermine N1-acetyltransferase

Hs.28491

1.92

0.09

HSI030F05

HTRA1

HtrA serine peptidase 1

Hs.501280

1.92

0.00

HSI088D11

CILP

Cartilage intermediate layer protein

Hs.442180

1.91

0.00

HSI040E09

MME

Membrane metallo-endopeptidase (CALLA, CD10)

Hs.307734

1.91

0.00

HSI028G12

PDGFRA

Platelet-derived growth factor receptor, alpha

Hs.74615

1.89

0.00

HSI060C05

FN1

Fibronectin 1

Hs.203717

1.89

0.00

HSI045G12

CXCL12

Chemokine ligand 12 (stromal cell-derived factor 1)

Hs.522891

1.88

0.00

  1. Shown are the first 40 upregulated genes from a paired SAM analysis, which identified 1,365 genes to be upregulated by aromatase inhibitor (AI) treatment below a local false discovery rate of 1% (LFDR). The genes are ranked according to their fold change.