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Table 1 Association of glutathione S-transferase (GST)M1 genotype and clinicopathological data of breast cancer patients studied

From: Glutathione S-transferase M1 null genotype: lack of association with tumour characteristics and survival in advanced breast cancer

   GSTM1  
Parameters Variables Present Null OR (95% Cl)
Age (years) >50 22 28  
  >50 17 25 1.99 (0.531-7.44)
Status Premenopausal 22 23  
  Postmenopausal 17 30 0.59 (0.22-1.61)
Clinical tumour size T2 15 16  
  T3 + T4 24 37 1.7 (0.62-4.52)
Clinical nodal involvement N0 14 11  
  N1 + N2 25 42 3.02 (0.97-9.89)
Histologic grade SBR1 8 6  
  SBR2 + 3 31 47 2.4 (0.66-9.02)
Hormone receptors HR- 17 19  
  HR+ 22 34 1.04 (0.38-2.80)
Pathological tumour size pT0 + pT1 19 26  
  pT2 + pT3 20 24 0.8 (0.32-2.08)
Involved nodes pN- 10 9  
  pN1+ pN3+ 29 54 2.05 (0.67-6.27)
p53 Normal 31 33  
  Mutated 8 20 2.7 (0.88-7.90)
  1. CI, confidence interval; OR, odds ratio.