Table 1 Association of glutathione S-transferase (GST)M1 genotype and clinicopathological data of breast cancer patients studied
GSTM1 | ||||
|---|---|---|---|---|
Parameters | Variables | Present | Null | OR (95% Cl) |
Age (years) | >50 | 22 | 28 | |
>50 | 17 | 25 | 1.99 (0.531-7.44) | |
Status | Premenopausal | 22 | 23 | |
Postmenopausal | 17 | 30 | 0.59 (0.22-1.61) | |
Clinical tumour size | T2 | 15 | 16 | |
T3 + T4 | 24 | 37 | 1.7 (0.62-4.52) | |
Clinical nodal involvement | N0 | 14 | 11 | |
N1 + N2 | 25 | 42 | 3.02 (0.97-9.89) | |
Histologic grade | SBR1 | 8 | 6 | |
SBR2 + 3 | 31 | 47 | 2.4 (0.66-9.02) | |
Hormone receptors | HR- | 17 | 19 | |
HR+ | 22 | 34 | 1.04 (0.38-2.80) | |
Pathological tumour size | pT0 + pT1 | 19 | 26 | |
pT2 + pT3 | 20 | 24 | 0.8 (0.32-2.08) | |
Involved nodes | pN- | 10 | 9 | |
pN1+ pN3+ | 29 | 54 | 2.05 (0.67-6.27) | |
p53 | Normal | 31 | 33 | |
Mutated | 8 | 20 | 2.7 (0.88-7.90) | |