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Figure 1 | Breast Cancer Research

Figure 1

From: Low E2F1 transcript levels are a strong determinant of favorable breast cancer outcome

Figure 1

Estrogen receptor and ERBB2 versus E2F1 expression levels. Scatter plots of estrogen receptor (ER) ESR1 and ERBB2 versus E2F1 expression levels in (a), (b) the Stiftung Tumorbank Basel data (STB) set and (c), (d) The Netherlands Cancer Institute (NKI) data set. Open circles, no metastasis; filled circles, metastasis. Vertical lines, cutoff values for the estrogen receptor (ER) and ERBB2 status, respectively; horizontal lines, 30th percentile for E2F1. Combined Kaplan–Meier analysis (metastasis-free survival) using the ER or ERBB2 status and E2F1 (30th percentile) in (e), (f) the STB data set and (g), (h) the NKI data set. Labels of the survival curves correspond to the groups as indicated on the respective scatter plot. CI, 95% confidence interval; HR, hazard ratio.

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