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Table 1 SNP tagging details and data for each gene

From: Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk

Gene SNP source Total SNPs with MAF > 0.05 Total SNPs after exclusion of African subjects No. of Tag SNPs selected for r2 > 0.8 Usable SNPs No. of SNPs tagged with rp2 > 0.8 (percent) No. of SNPs tagged with rp 2 > 0.5 (percent) No. of SNPs tagged with r2S > 0.8 (percent)
ATM EGP 75 69 9 9 64 (92) 69 (100) 65 (94)
BRCA1 EGP 123 113 8 5 67 (59) 109 (96) 77 (68)
BRCA2 EGP 113 91 22 16 53 (58) 86 (95) 61 (67)
CHEK2 HAPMAP 30 N/A 10 10 16 (53) 20 (67) 22 (73)
TP53 EGP 46 39 6 5 24 (61) 35 (90) 31 (79)
  1. EGP, NIEHS Environmental Genome Project; MAF, minor allele frequency; SNP, single nucleotide polymorphism.