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Table 5 Frequencies of CBC patients carrying apathogenic DNA-damage repair pathway mutation

From: Identification of women with an increased risk of developing radiation-induced breast cancer: a case only study

Interval (years) All CBC patients Previous RT No RT Carriers versus non-carriers
  n Percentage n Percentage n Percentage OR for CBC after RT 95% CI p
1–5 (n = 66) 15/66 22.7 12/49 24.5 3/16 18.8 1.41 0.34–5.78  
>5 (n = 181) 36/181 19.9 29/120 24.1 7/62 11.3 2.51 1.03–6.10 0.049
  1. All contralateral breast cancer (CBC) patients, and patients stratified by previous radiation exposure are presented, according to interval between first and second primary breast cancer (less than 5 and more than 5 years). Odds ratio (OR) and 95% confidence interval (CI) are given for mutation carriers versus non-carriers to develop radiation-associated breast cancer. RT, radiation treatment.
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