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Table 4 Frequencies of CBC patients carrying apathogenic DNA-damage repair pathway mutation

From: Identification of women with an increased risk of developing radiation-induced breast cancer: a case only study

Age (years) All CBC patients Previous RT No RT Carriers versus non-carriers
  n Percentage n Percentage n Percentage OR for CBC after RT 95% CI
<40 (n = 91) 22/91 24 19/67 28 3/24 12 2.77 0.74–10.39
40–50 (n = 156) 29/156 18.6 22/102 21.6 7/54 12.9 1.85 0.73–4.65
  1. Results for all contralateral breast cancer (CBC) patients, and patients stratified by previous radiation exposure, are presented, according to age at diagnosis of first primary breast cancer (before the age of 40 years or between 40 and 50 years of age). Odds ratio (OR) and 95% confidence interval (CI) are given for mutation carriers versus non-carriers to develop radiation-associated breast cancer. RT, radiation treatment.
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