Parameter | All CBC patients (n = 247) | Previous RT (n = 169) | No RT (n = 78) | Carriers versus non-carriers | |||||
---|---|---|---|---|---|---|---|---|---|
 | n | Percentage | n | Percentage | n | Percentage | OR for CBC after RT | 95% CI | p |
DDRP mutated | 51 | 21 | 41 | 24.3 | 10 | 12.8 | 2.18 | 1.03–4.62 | 0.043 |
All patients with only a pathogenic DDRP mutation | 37 | 15 | 29 | 17.2 | 8 | 10.3 | 1.8 | 0.79–4.17 |  |
Patients with both a pathogenic DDRP and an ATM missense mutation | 14 | 5.7 | 12 | 7.1 | 2 | 2.6 | 2.90 | 0.63–13.30 |  |
Patients with only an ATM missense mutation | 29 | 11.7 | 21 | 12.4 | 8 | 10.3 | 1.24 | 0.52–2.94 |  |