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Table 1 Tumour and patient characteristics, by DDRP mutation carrier status and previous RT exposure

From: Identification of women with an increased risk of developing radiation-induced breast cancer: a case only study

Characteristic

Mutation positive (n = 51)

Mutation negative (n = 196)

 

Previous RT

No previous RT

Previous RT

No previous RT

Age at first BC, years

40.3

42.4

41.4

42.3

Age at second BC, years

48.1

51.8

51.1

54.2

Chemotherapy, n (percentage)

11 (27)

1 (10)

28 (22)

5 (7)

Tumour size, cm

1.8

2.9

2.2

2.3

Lymph node positive, n (percentage)

12 (29)

1 (10)

41 (32)

4 (6)

RT dosea, Gy

    

   Mean (range)

1.49 (0.27–3.73)

 

1.55 (0.24–5.61)

 

   Median

1.32

 

1.40

 

   Third quartile

1.79

 

1.89

 
  1. DDRP, DNA-damage repair pathway; BC, breast cancer; RT, radiation treatment. aRadiation dose to the site of the breast where the tumour had developed.