Identification of typical medullary breast carcinoma as a genomic sub-group of basal-like carcinomas, a heterogeneous new molecular entity

Table 4 Regions of gains and losses, significantly different between the MBC and BLC groups

Chromosome	Region	Alteration	Start position (bp)	End position (bp)	MBC	BLC	Median frequency (percentage)	p
3	3q27	G	159,935,817	163,800,681	G		30.3	0.049
4	4p15.2-15.1	L	27,441,218	30,744,383	L		34.8	0.025
9	9p24	G	628,053	2,280,507	G		30.3	0.0146
9	9p24	G	3,447,196	7,740,086	G		30.3	0.022
9	9p13	G	36,830,822	40,205,823	G		31.8	0.011
10	10p14-13	G	10,572,971	15,532,695	G		53.0	0.018
16	16q24	G	85,913,563	88,552,226	G		25.8	0.01525
X	Xq12–13	L	66,582,902	71,458,243		L	38.5	0.001

MBC, medullary breast carcinoma; BLC, basal-like carcinoma; G, gain; L, loss. Start and end coordinates of the regions are indicated in bp (May 2004 working draft).

ISSN: 1465-542X