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Table 2 Immunophenotypes of basal-like carcinomas and medullary breast carcinomas

From: Identification of typical medullary breast carcinoma as a genomic sub-group of basal-like carcinomas, a heterogeneous new molecular entity

Marker

 

Medullary breast carcinomas (n = 33)

Basal-like carcinomas (n = 26)

p

ER

+

0 (0)

0 (0)

 
 

-

33(100)

26 (100)

-

PR

+

0 (0)

0 (0)

 
 

-

33(100)

26 (100)

-

ERBB2

+

0 (0)

0 (0)

 
 

-

32 (100)

25 (100)

-

 

n.d.

1

1

 

TP 53

+

20 (61)

12 (48)

 
 

-

13 (39)

13 (52)

n.s.

 

n.d.

0

1

 

KRT 5/6

+

30 (94)

14 (56)

 
 

-

2 (6)

11 (44)

0.0004

 

n.d.

1

1

 

KRT 8/18

+

30 (94)

19 (76)

 
 

-

2 (6)

6 (24)

0.06

 

n.d.

1

1

 

KRT 14

+

17 (55)

18 (78)

 
 

-

14 (45)

5 (22)

n.s.

 

n.d.

2

3

 

EGFR

+

22 (69)

10 (45)

 
 

-

10 (31)

12 (55)

0.06

 

n.d.

1

4

 

KIT

+

19 (59)

12 (60)

 
 

-

13 (41)

8 (40)

n.s.

 

n.d.

1

6

 
  1. n.d., not determined; n.s., not significant. Numbers in parentheses are percentages.