SNP

Genotype

n

Mean percentage MD^{a}

p for trend^{b}


1

C/C

2

19.1

0.13


C/T

71

29.5
 

T/T

1,035

26.5
 
2

A/A

20

29.1

0.07


A/G

308

25.0
 

G/G

748

27.4
 
3

A/A

51

27.3

0.74


A/G

388

26.6
 

G/G

662

26.5
 
4

A/A

23

25.9

0.89


A/C

284

26.7
 

C/C

816

26.8
 
5

G/G

47

24.7

0.74


C/G

403

26.6
 

C/C

657

26.8
 
6

G/G

88

24.3

0.05


A/G

419

26.4
 

A/A

569

27.6
 
7

A/A

7

20.1

0.007


A/G

155

24.7
 

G/G

934

27.4
 
8

T/T

20

29.3

0.18


G/T

255

27.9
 

G/G

776

26.4
 
9

G/G

36

19.6

<0.0001


C/G

325

24.8
 

C/C

730

27.9
 
10

G/G

19

25.3

0.83


G/C

262

27.4
 

C/C

809

26.6
 
11

A/A

117

23.2

0.0004


G/A

469

26.4
 

G/G

503

28.2
 
12

C/C

59

24.3

0.16


C/G

425

26.5
 

G/G

605

27.2
 
13

G/G

270

27.0

0.60


A/G

570

26.6
 

A/A

278

26.8
 
14

G/G

26

26.1

0.82


A/G

320

26.3
 

A/A

750

26.9
 

^{a}Multivariateadjusted models including age (continuous), body mass index (continuous), alcohol consumption (category), age at first birth/parity, history of benign breast disease (yes/no), family history of breast cancer (yes/no), menopausal status/postmenopausal hormone use (premenopausal, postmenopausal never user, postmenopausal current user, postmenopausal past user); ^{b}
p for trend based on inclusion of genotype as an ordinal variable in models with squareroottransformed mammographic density as the dependent variable. Results in bold are significant (p ≤ 0.05).