Skip to main content

Table 1 Tumorigenesis in short-term hormone-treated mice

From: Hormone-induced protection of mammary tumorigenesis in genetically engineered mouse models

Experiment

Group

Tumors/transplants (percentage)

Percentage inhibition

Experiment duration (weeks)

1/1A

Untreated

16/66 (24)

-

45

 

E/P (5–7)

2/66 (03)a

87.5

45

2

Untreated

10/20 (50)

-

48

 

E/P (5–7)

3/20 (15)a

70

48

 

E/P (23–25)

4/20 (20)a

60

48

 

Tamoxifen (11–24)

0/20 (0)a

100

48

3

Untreated, trans. (3)

9/20 (45)

-

58

 

E/P (5–7), trans. (3)

3/15 (20)a

56

58

 

Untreated, trans. (11)

9/20 (45)

-

58

 

E+P (5–7), trans. (11)

4/20 (20)a

56

58

4

Untreated

15/15b (100)

 

24

 

E/P

6/15b (37) a

63

32

 

E

5/15b (33) a

67

32

  1. E, estrogen; P, progesterone; trans., transplantation. a p < 0.05; bin this experiment, the column refers to the number of tumor-bearing mice/total number of mice.