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Table 1 Tumorigenesis in short-term hormone-treated mice

From: Hormone-induced protection of mammary tumorigenesis in genetically engineered mouse models

Experiment Group Tumors/transplants (percentage) Percentage inhibition Experiment duration (weeks)
1/1A Untreated 16/66 (24) - 45
  E/P (5–7) 2/66 (03)a 87.5 45
2 Untreated 10/20 (50) - 48
  E/P (5–7) 3/20 (15)a 70 48
  E/P (23–25) 4/20 (20)a 60 48
  Tamoxifen (11–24) 0/20 (0)a 100 48
3 Untreated, trans. (3) 9/20 (45) - 58
  E/P (5–7), trans. (3) 3/15 (20)a 56 58
  Untreated, trans. (11) 9/20 (45) - 58
  E+P (5–7), trans. (11) 4/20 (20)a 56 58
4 Untreated 15/15b (100)   24
  E/P 6/15b (37) a 63 32
  E 5/15b (33) a 67 32
  1. E, estrogen; P, progesterone; trans., transplantation. a p < 0.05; bin this experiment, the column refers to the number of tumor-bearing mice/total number of mice.