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Table 5 Correlation of c-met, Sdc1 and E-cad expression with angiogenic and lymphangiogenic factors

From: An expression signature of syndecan-1 (CD138), E-cadherin and c-met is associated with factors of angiogenesis and lymphangiogenesis in ductal breast carcinoma in situ

 

c-met

E-cad

Sdc1

 

Negative (n = 73)

Positive (n = 69)

P

Negative (n = 48)

Positive (n = 101)

P

Negative (n = 42)

Positive (n = 105)

P

VEGF-A

36.2%

53.8%

0.040

26.2%

52.0%

0.005

55%

41.6%

0.149

Flt-1

18.6%

7.7%

0.063

14.3%

11.5%

0.642

12.8%

12.5%

0.959

KDR

48.4%

63.1%

0.094

47.4%

56.4%

0.347

45.7%

58.3%

0.198

VEGF-C

84.5%

94.1%

0.068

80.4%

91.8%

0.048

80.5%

91.5%

0.061

Flt-4

92.9%

98.6%

0.099

95.1%

97.0%

0.584

90.0%

97.2%

0.071

ET-1

47.7%

59.7%

0.176

52.4%

48.9%

0.709

47.4%

51.6%

0.661

ETAR

56.7%

92.6%

<0.001

53.8%

86.9%

<0.001

70.3%

79.0%

0.277

ETBR

23.4%

57.4%

<0.001

30.8%

43.3%

0.177

31.6%

47.0%

0.102

BFGF

17.4%

11.9%

0.394

10.0%

13.4%

0.583

18.9%

11.4%

0.250

FGFR1

89.1%

98.4%

0.028

92.3%

95.9%

0.394

91.4%

96.0%

0.287

  1. bFGF, basic fibroblast growth factor; E-cad, E-cadherin; ET, endothelin; ETA/BR, endothelin A/B receptor; FGFR, fibroblast growth factor receptor; Sdc, syndecan; VEGF, vascular endothelial growth factor.